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Invitrogen™ Human PAPPA Recombinant Protein

Product Code. 11579011 Shop All Thermo Scientific Products
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Product Code. 11579011 Supplier Invitrogen™ Supplier No. RP75696

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Description

Recombinant Protein

This product contains purified recombinant human Pregnancy Associated Plasma Protein-1 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterottetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (trisomy 21).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q13219
Concentration 3.0 mg/mL
For Use With (Application) Control, Western Blot
Formulation 20 mM tris HCl, 4 M urea with 50% glycerol and no preservative; pH 8
Gene ID (Entrez) 5069
Name Human PAPPA
Quantity 1 mg
Source E. coli
Immunogen N/A
Regulatory Status RUO
Gene Alias 8430414N03Rik; ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4 ase; IGFBP-4 ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; insulin-like growth factor-dependent IGF-binding protein 4 protease; PAG1; PAPA; PAPP A; PAPPA; PAPP-A; PAPPA1; Pappalysin; pappalysin 1; pappalysin-1; pregnacy-associated plasma protein A; pregnancy-associated plasma protein A; pregnancy-associated plasma protein A, pappalysin 1; RP11-45A16.1
Common Name PAPPA
Gene Symbol PAPPA
Conjugate Unconjugated
Species E. coli
Recombinant Recombinant
Protein Tag His-tag
Sequence Amino acids Arg81-Asp271 containing an N-terminal His-tag
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Protein Subtype Recombinant
Purity or Quality Grade >95%, by SDS-PAGE under reducing conditions
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