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STEMCELL Technologies Human Recombinant GDF-5

Product Code. 17149591
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. 17149591

Brand: STEMCELL Technologies 78111.1

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This item is not returnable. View return policy

Description

Growth differentiation factor 5

  • Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) subclass of the transforming growth factor beta (TGF-β) superfamily
  • It binds a receptor complex comprising BMPR1B and BMPR2, which then activates the SMAD signaling pathway (Carreira et al.; Nishitoh et al.; Osório et al.) GDF-5 enhances chondrogenic differentiation of mesenchymal stem cells, skeletogenesis, and dendrite growth during development (Coleman et al.; Francis-West et al.) Studies in rat demonstrated that GDF-5 regulates patterning, neurogenesis, astrogliogenesis, and neuronal specification (Gajavelli et al.; Krieglstein et al.; O'Keeffe et al.)

Specifications

Name BMP-14, Bone morphogenic protein 14, CDMP-1, Growth differentiation factor 5
Quantity 100 μg
Cell Type Endoderm, PSC-Derived; Neural Stem and Progenitor Cells
Purity or Quality Grade ≥95%
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