missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. STEMCELL Technologies Human Recombinant GDNF, ACF

STEMCELL Technologies Human Recombinant GDNF, ACF

Product Code. 17129661
Encompass_Preferred
Click to view available options
Quantity:
10 μg
100 μg
1000 μg
Unit Size:
1000µg
100µg
10µg
This item is not returnable. View return policy

Product Code. 17129661

Brand: STEMCELL Technologies 78139

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Glial cell line-derived neurotrophic factor

  • Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor and a member of the tumor growth factor (TGF)-beta superfamily
  • The GDNF family of growth factors also includes neurturin, persephin, and artemin, which have seven conserved cysteine residues called cysteine-knot
  • GDNF family ligands signal through binding to specific GDNF-family receptor-α (GFRα) co-receptors and activate the RET receptor tyrosine kinase
  • Four different forms of GFRα co-receptors have been characterized (GFRα 1-4) out of which GDNF binds specifically to GFRα1 prior to forming a complex with RET
  • GDNF is known to promote survival and morphological differentiation of midbrain dopaminergic neurons in both in vivo and in vitro studies and increase their high-affinity dopamine uptake
  • GDNF has also been shown to have restorative effects on dying dopaminergic neurons in response to degenerative toxins

Specifications

Name Astrocyte-derived trophic factor, ATF, ATF1, ATF2, Glial cell-derived neurotrophic factor
Quantity 10 μg
Cell Type Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons
Purity or Quality Grade ≥95%
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.