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Invitrogen™ Human RNF43 (aa 298-427) Control Fragment Recombinant Protein

Product Code. 30193705
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30193705

Brand: Invitrogen™ RP89654

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52512 (PA5-52512. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q68DV7
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 54894
Name Human RNF43 (aa 298-427) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 4732452J19Rik; E3 ubiquitin-protein ligase RNF43; RGD1305204; RING finger protein 43; RING-type E3 ubiquitin transferase RNF43; RNF124; Rnf43; URCC
Common Name RNF43
Gene Symbol RNF43
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence CVDPWLHQHRTCPLCMFNITEGDSFSQSLGPSRSYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQEPGMGPRHHRFPRAAHPRAPGEQQRLAGAQHPYAQGWGLSHLQSTSQH
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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