missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 30279887

Tocris Bioscience™ IBG3

Product Code. 30279887
Click to view available options
:
2 mg
This item is not returnable. View return policy

Product Code. 30279887

Brand: Tocris Bioscience™ 8129/2

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Potent molecular glue Degrader of BET proteins BRD4 and BRD2

IBG3 is a very potent JQ1 -containing molecular glue Degrader of BET proteins BRD4 and BRD2 (DC50 values are 6.7 pM and 8.6 pM respectively). Induces proximity between BRD4 and DCAF16 to form a ternary complex (EC50 = 32 nM).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material tert-Butyl 2-((S)-4-(4-((4'-((S)-6-(2-(tert-butoxy)-2-oxoethyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-[1,1'-biphenyl]-4-carboxamido)methyl)phenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]dia
Quantity 2 mg
Target Molecular Glues
Molecular Formula C54H57N9O5S2
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.