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IL-13 Rat anti-Mouse, Biotin, Clone: eBio1316H, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-7135-85

Additional Details : Poids : 0.25000kg

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Product Code. 15380040

  • 265.00€ / 500µg


Expédition estimée
02-10-2020
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Description

Description

A suitable range of concentrations of this antibody for ELISA detection is 0.25-1 µg/mL. A standard curve consisting of doubling dilutions of the recombit standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate. For intracellular staining of mouse IL-13, the fluorochrome labelled eBio13A antibody is recommended. Filtration: 0.2 μm post-manufacturing filtered. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
Specifications

Specifications

IL-13
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P20109
Interleukin-13, ALRH antibody, NC30 antibody, P600 antibody
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
ELISA
eBio1316H
Biotin
Il13
Liquid
Il13
IgG1, kappa
500 μg
4° C, do not freeze
Primary
16163
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