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IL-5 Monoclonal Antibody (JES1-5A10), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
138.00€ - 323.00€
Specifications
Antigen | IL-5 |
---|---|
Clone | JES1-5A10 |
Concentration | 0.5 mg/mL |
Applications | ELISA |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15370020
|
Affymetrix eBioscience
13-7059-81 |
50 μg |
138.00€
50µg |
Estimated Shipment: 29-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
15380020
|
Affymetrix eBioscience
13-7059-85 |
500 μg |
323.00€
500µg |
Estimated Shipment: 29-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Description: The JES1-5A10 antibody reacts with human interleukin-5 (IL-5), also known as BCDF-alpha and eosinophil differentiation factor (EDF). This 15-20 kDa cytokine is secreted by T cells and exists a homodimer. Applications Reported: JES1-5A10 has been reported for use in detection of human IL-5 by ELISA. Applications Tested: The JES1-5A10 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of human Interleukin-5 (IL-5) in combination with the purified TRFK5 (14-7052) antibody for capture and recombinant human IL-5 (14-8059) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 500 pg/mL - 4 pg/mL should be included in each ELISA plate. Filtration: 0.2 μm post-manufacturing filtered.
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.Specifications
IL-5 | |
0.5 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF | |
Il5 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Il5 |
JES1-5A10 | |
ELISA | |
Biotin | |
Rat | |
Human | |
P05113 | |
3567 | |
IgG2a κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.