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IL-5 Monoclonal Antibody (TRFK4), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-7051-85
Additional Details : Weight : 0.25000kg
Description
Description: The TRFK4 antibody reacts with mouse interleukin-5 (IL-5), also known as BCDF-alpha and eosinophil differentiation factor (EDF). This 15-20 kDa cytokine is secreted by Th2 cells and exists a homodimer. Applications Reported: TRFK4 has been reported for use in detection of mouse IL-5 by ELISA. Applications Tested: The TRFK4 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of mouse Interleukin-5 (IL-5) in combination with the purified TRFK5 (14-7052) antibody for capture and recombinant mouse IL-5 (14-8051) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate. Filtration: 0.2 μm post-manufacturing filtered.
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.Specifications
IL-5 | |
Monoclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P04401 | |
Il5 | |
Affinity chromatography | |
RUO | |
16191 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Immunostaining | |
TRFK4 | |
Biotin | |
Il5 | |
B-cell differentiation factor I; B-cell growth factor II; BCGF-II; colony-stimulating factor, eosinophil; cytotoxic T-lymphocyte inducer; EDF; Eosinophil differentiation factor; IL5; IL-5; ILN; Interleukin; Interleukin 5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); Interleukin5; interleukin-5; T-cell replacing factor; TRF | |
Rat | |
500 μg | |
Primary | |
Mouse | |
Antibody | |
IgG2a κ |
For Research Use Only.