Integrin beta 5 Mouse anti-Hamster, Human, Mouse, Clone: KN52, eBioscience™
Mouse Monoclonal Antibody
Marque: Affymetrix eBioscience 14-0497-82
Informations supplémentaires : Poids : 0.01000kg
DescriptionIntegrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell-surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in-groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N-terminal extracellular domain that binds the ECM ligand and a small C-terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.
|Integrin Beta 5|
|PBS with 0.09% sodium azide; pH 7.2|
|CD61, GP3A, GPIIIa|
|Hamster, Human, Mouse|
|100765378, 16419, 3693|
For Research Use Only.