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Invitrogen™ IRAK3 Recombinant Human Protein
This IRAK3 Recombinant Human Protein (full length) was expressed in insect cells.
Brand: Invitrogen™ A30975
Additional Details : Weight : 0.10000kg
Description
- This IRAK3 recombinant human protein (full length) was expressed in insect cells
- IRAK3 serine/threonine kinase, or interleukin-1 receptor-associated kinase 3, is a member of the interleukin-1 receptor-associated kinase protein family
- This family is resposible for essential components of the Toll/IL-R immune signal transduction pathways
- IRAK3 is primarily expressed in monocytes and macrophages
- It functions as a negative regulator of Toll-like receptor signaling
- IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis
- Mutations in IRAK3 are associated with a susceptibility to asthma
- IRAK3 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the LanthaScreen™ Eu Kinase Binding assay
- Available in multiple pack sizes for convenient use
Specifications
| AAH57800 | |
| 10 µg | |
| Full Length | |
| GST Tag | |
| Dry Ice | |
| Kinases & Inhibitors | |
| Liquid | |
| Human |
| 94.0 kDa | |
| IRAK Kinase Family | |
| Yes | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol | |
| Baculovirus | |
| Recombinant, Full Length | |
| Kinase Assay |