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Kanamycin monosulfate

Code produit 15493879
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Règlementaire: Une licence est requise pour acheter ce produit; ARRETE ROYAL DU 12 AVRIL 1974.
Code produit 15493879 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur J61272.22
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Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.
Règlementaire: Une licence est requise pour acheter ce produit; ARRETE ROYAL DU 12 AVRIL 1974.

Description

Le monosulfate de kanamycine, numéro CAS 25389-94-0, est un sel de sulfate d’aminoglucoside présentant une activité antibactérienne.

Antibiotic. Inhibits translocation during protein biosynthesis.Kanamycin monosulfate acts as an antibiotic and used to treat various infections. It is involved in the translation of prokaryotic ribosomes arises due to bacterial cell death. It is used as a selective agent in molecular biology in order to isolate transformants that are expressing a kanamycin resistance gene.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Kanamycin monosulfate is the sulfate salt form of kanamycin A
  • It was isolated from Streptomyces kanamyceticus
  • This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

  • Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
  • This compound is also involved in translating prokaryotic ribosomes
  • In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 25389-94-0
Formule moléculaire C18H38N4O15S
Poids moléculaire (g/mol) 582.575
Numéro MDL MFCD00070253
Clé InChI OOYGSFOGFJDDHP-IZQIRFRQSA-N
Synonyme Kanamycin A
CID PubChem 134129479
Nom IUPAC (2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O

Specifications

Nom chimique ou matériau Kanamycin monosulfate
Type Kanamycin Monosulfate
Forme physique Powder
Couleur Blanc
Quantité 100 g
Merck Index 14,5281
Informations sur la solubilité Dissolve in water at 10mg/ml.Soluble in water.
Poids de la formule 582.58

RUO – Research Use Only

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