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CD117/c-Kit/SCF-Receptor Ab-3 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments.

Brand:  Epredia MS-289-P0

Additional Details : Weight : 0.00170kg

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Product Code. 12670827

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.


Description

Description

c-kit is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (SCF). It is expressed in many tissues and cells. C-kit/SCf is involved in development of several lineages of stem cells, such as germ cells, neural crest-derived melanocytes and hematopoietic precursor cells. Ab-3 does not interfere with the binding of SCF to c-kit

Host Species: Mouse

Clone: K45

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Extracellular second N-terminus Ig-like domain of c-kit

Immunogen: Recombinant human extracellular c-kit fragment

Molecular Weight: 145kDa

Positive Control: Skin, GI Stromal Tumor (GIST)

Cellular Localization: Membrane/cytoplasmic

Recommended for:

  • Immunohistochemistry (Frozen or fixed in methacarn or Stieve's and embedded in paraffin)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

CD117/c-Kit/SCF-Receptor Ab-3
Monoclonal
200μg/mL
Mouse
100 μL
Primary
Concentrated
Immunofluorescence, Immunohistochemistry (Frozen)
K45
Unconjugated
Recombinant human extracellular c-kit fragment
RUO
Human
IgG2a
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