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  7. 12693647

Cyclin D1 Rabbit Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cyclin D1, Rabbit Monoclonal Antibody.

Brand:  Epredia RM-2113-S0

Additional Details : Weight : 0.00010kg

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Product Code. 12693647

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.


Description

Description

Cyclin D1 or PRAD-1 or bcl-1 is a key cell cycle regulator. It functions in association with cdk4 and/or cdk6 by phosphorylating the retinoblastoma protein that releases transcription factors to initiate DNA replication. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. In lymphoid lesions, with the exception of few rare diseases, it is specific for mantle cell lymphoma (MCL).

Host Species: Rabbit

Clone: EPR2241IHC

Isotype: IgG

Species Reactivity: Human. Others not tested.

Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1

Molecular Weight: 36 kDa

Positive Control: Mantle cell lymphoma

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
Specifications

Specifications

Cyclin D1
EPR2241IHC
Rabbit
100 μL
Human
Immunohistochemistry
Unconjugated
A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1
Primary
Supernatant
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