Thermo Scientific™ Lab Vision™ Cyclin D1, Rabbit Monoclonal Antibody
Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Cyclin D1, Rabbit Monoclonal Antibody.
Brand: Thermo Scientific™ RM-2113-R7
Additional Details : Weight : 1.00000kg
Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Cyclin D1, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.Cyclin D1 or PRAD-1 or bcl-1 is a key cell cycle regulator. It functions in association with cdk4 and/or cdk6 by phosphorylating the retinoblastoma protein that releases transcription factors to initiate DNA replication. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. In lymphoid lesions, with the exception of few rare diseases, it is specific for mantle cell lymphoma (MCL).
Host Species: Rabbit
Species Reactivity: Human. Others not tested.
Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1
Molecular Weight: 36 kDa
Positive Control: Mantle cell lymphoma
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
|Ready-to-use for IHC (UVLP)|
|Ready to Use|
|A synthetic peptide corresponding to residues near the C-terminus of human Cyclin D1|