missing translation for 'onlineSavingsMsg'
Learn More

Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody.

Brand:  Thermo Scientific™ MS-269-P1ABX

Additional Details : Weight : 1.00000kg

 View more versions of this product

Product Code. 12630757

  • 421.00€ / 100µL


Estimated Shipment
20-05-2021
Add to basket

Description

Description

Ensure accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 225

Isotype: IgG1

Species Reactivity: Human, Chimpanzee and Monkey. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: Purified EGFR from A431 cells

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Immunoprecipitation (Native only)
  • Blocks EGF/TGFα-Induced Activation of EGFR
  • Arrests Tumor Growth in vivo
  • Inhibits Binding of Ab-1 (clone 528) to EGFR

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Epidermal Growth Factor Receptor/EGFR Ab-2
Monoclonal
1mg/mL
Concentrated
Purified EGFR from A431 cells
100μL
EGFR Family
Primary
Human, Non-human Primate
Immunoprecipitation
225
Unconjugated
Murine
IgG1
RUO
Primary
Monoclonal
Videos
SDS
Documents