Thermo Scientific™ Lab Vision™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.
Brand: Thermo Scientific™ MS-391-R7
Additional Details : Weight : 1.00000kg
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments with Thermo Scientific™ Estrogen Receptor Ab-12, Mouse Monoclonal Antibody.
The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Host Species: Mouse
Species Reactivity: Human and Rat. Others not known.
Immunogen: Recombinant full-length estrogen receptor protein
Molecular Weight: 67 kDa
Positive Control: MCF-7 cells, Breast CA
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
USA: RUO; Int'l: RUO
|Estrogen Receptor Ab-12|
|Recombinant full length estrogen receptor protein|
|Steroids Hormones and Growth Factors|
|Ready-to-use for IHC (UVLP)|