Thermo Scientific™ Lab Vision™ Granzyme B Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Granzyme B Ab-1, Mouse Monoclonal Antibody.
Brand: Thermo Scientific™ MS-1157-S1
Additional Details : Weight : 0.00190kg
Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Granzyme B Ab-1, Mouse Monoclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified. One of these, human granzyme B, is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. Exocytosis of granzyme-containing granules in the cytoplasm of the target cell leads to the induction of DNA fragmentation and apoptosis.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Immunogen: Recombinant protein encoding the N-terminus of the mature granzyme B
Molecular Weight: 32 kDa
Positive Control: Hodgkin's lymphoma, Tonsil
Cellular Localization: Granular cytoplasmic
- Immunohistochemistry (Formalin/paraffin only)
|Granzyme B Ab-1|
|Recombinant protein encoding the N-terminus of the mature granzyme B|