missing translation for 'onlineSavingsMsg'
Learn More
Learn More
GeneBLAzer™ LXRβ-UAS-bla HEK 293T Cells
GeneBLAzer™ LXRβ-UAS-bla HEK 293T Cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-beta (LXR beta).
Brand: GeneBLAzer™ K1699
Additional Details : Weight : 0.01000kg
Description
- Alternate Agonists: DHT
- Antagonists: Cyp Acetate, OHF, Spirolactone
- Primary Agonist: R1881
- LXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-beta (LXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line. GeneBLAzer™UAS-bla HEK 293T cells stably express a beta-lactamase reporter gene under the transcriptional control of an upstream activator sequence (UAS). When an agonist binds to the LBD of the GAL4 (DBD)-LXR beta (LBD) fusion protein, the protein binds to the UAS, resulting in expression of beta-lactamase. Division Arrested (DA) cells are available in two configurations- an Assay Kit (which includes cells and sufficient substrate to analyze 1 x 384-well plate), and a tube of cells sufficient to analyze 10 x 384-well plates. LXR beta-UAS-bla HEK 293T 293 cells are functionally validated for Z' and EC50 concentrations of TO901317. In addition, cells have been tested for assay performance under variable conditions, including DMSO concentration, cell number, stimulation time, and substrate loading time (data available upon request).
Specifications
| Liquid Nitrogen | |
| Nuclear Receptors | |
| Dividing Cells |
| Fluorescent | |
| 2 x 106 Cells |