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  4. Invitrogen™ Human MAP2K2 (MEK2), His Tag Recombinant Protein

Invitrogen™ Human MAP2K2 (MEK2), His Tag Recombinant Protein

Product Code. 11593467
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Quantity:
1 mg
10 μg
Unit Size:
10µg
1mg
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Product Code. 11593467

Brand: Invitrogen™ PV3615

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that is known to play a critical role in mitogen growth factor signal transduction. Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P36507
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 150mM NaCl, 0.5mM EDTA, 50% glycerol, 0.02% Triton X-100, 2mM DTT and no preservative; pH 7.5
Gene ID (Entrez) 5605
Molecular Weight (g/mol) 49.5 kDa
Name Human MAP2K2 (MEK2), His Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45
Common Name MEK2
Gene Symbol MAP2K2
KinaseFamily STE7 Kinase Family
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Kinase Group Ser⁄Thr Kinases: STE Group
Shipping Condition Dry Ice
System Compatibility Z'-LYTE™, Omnia™ Bulk Substrate
Target Entry MAP2K2
Target Gene mitogen-activated protein kinase kinase 2
Expression System Baculovirus
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Protein Subtype Serine/Threonine Kinases
Research Category Signal Transduction
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