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Eurofins DiscoverX Mer Protein, Active

Product Code. 17300624
Encompass_Preferred
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17300624

Brand: Eurofins DiscoverX 14728

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This item is not returnable. View return policy

Description

Active, N-terminal GST-tagged, recombinant, human Mer, amino acids 557-882, for use in Kinase Assays.

Mer Protein is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

GenBank NM_006343. The recombinant protein contains the amino acid substitutions H628Q and R794A with reference to NM_006343. H628Q is reported inGenBank AA398845 and BG566419, R794A is reported inGenBank BG109051 and BX280572.

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 64.4 kDa
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal GST
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Truncated
Purity or Quality Grade ≥63%
Protein Mer, active
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