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Invitrogen™ Human MET (cMET) [Y1235D], GST Tag Recombinant Protein

Human MET (cMET) [Y1235D], GST Tag Recombinant Protein

Brand:  Invitrogen™ A33505

Additional Details : Weight : 0.01000kg

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Product Code. 15920413

  • 524.00€ / 10µg
Estimated Shipment: 19-03-2024
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Description

Description

  • This MET (cMET) Y1235D recombinant human protein (956-end) was expressed in insect cells
  • MET receptor tyrosine kinase is a proto-oncogene that encodes a transmembrane growth factor receptor
  • MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue
  • Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity
  • MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers
  • It has also been shown to be involved in tumor cell migration and invasion
  • MET (Y1235D) is one of the native mutant forms of MET
  • MET (cMET) Y1235D recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
  • Validated for use with the Z'-LYTE™ assay
  • Available in multiple pack sizes for convenient use
Specifications

Specifications

NP_000236.2
75.4 kDa
METs (HGFRs)
Human
GST Tag
Dry Ice
Kinases & Inhibitors
Liquid
Kinase Assay
10 μg
aa 956 - 1390
Recombinant
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol
Baculovirus
Recombinant, Active, Cytoplasmic, Mutant
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