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Tocris Bioscience™ MK 386

Description
Potent and selective human type 1 5α-reductase inhibitor (5αR1, IC50 = 0.9 nM). Exhibits 100-fold selectivity for 5αR1 over 5αR2 (IC50 = 154 nM). Supresses human serum and sebum dihydrotestosterone (DHT) levels in a dose-dependent manner without affecting semen DHT concentrations. Orally active.
Specifications
Specifications
| CAS | 158493-17-5 |
| Quantity | 1 mg |
| Solubility | Soluble to 100mM in DMSO |
| Molecular Formula | C28H49NO |
| Formula Weight | 415.69 |
| Physical Form | Oil |
| Purity | >98% |
| Molecular Weight (g/mol) | 415.706 |
| Chemical Name or Material | (4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-7-[(1R)-1,5-Dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-2H- |
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