missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. Gibco™ Mouse CXCL13 (BLC/BCA-1) Recombinant Protein, PeproTech®

Gibco™ Mouse CXCL13 (BLC/BCA-1) Recombinant Protein, PeproTech®

Product Code. 17820253
Click to view available options
Quantity:
1 mg
100 μg
20 μg
250 μg
5 μg
50 μg
500 μg
Unit Size:
100µg
1mg
20µg
250µg
500µg
50µg
5µg
This item is not returnable. View return policy

Product Code. 17820253

Brand: Gibco™ 25024250UG

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in the secondary lymphoid organs. It preferentially promotes the migration of B lymphocytes (both B-1 and B-2) to the follicles of the spleen, lymph nodes, and Peyer's patches. It is produced by macrophages, and in mouse the highest constitutive producers include large peritoneal macrophages, Kuppfer cells and lung macrophages (both CD11c+ and CD11c-). The cellular ligand for CXCL13 is CXCR5 also known as BLR-1 (Burkitt’s Lymphoma Receptor 1). CXCR5 is expressed on B cells, Tfh cells and, to a lower degree, some memory T cell populations. CXCL13 plays an important role in the development of chronic lymphocytic leukemia (CCL). CXCL13 is also a plasma biomarker for germinal center activity and generation of broadly neutralizing antibodies against HIV.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O55038
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 55985
Molecular Weight (g/mol) 9.8 kDa
Name Mouse CXCL13 (BLC/BCA-1)
Quantity 250 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias 4631412M08Rik; Angie; ANGIE2; B cell-attracting chemokine 1; b lymphocyte chemoattractant; BCA1; BCA-1; B-cell chemoattractant; B-cell-attracting chemokine 1; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1); BLC; BLR1L; B-lymphocyte chemoattractant; C Cmotif chemokine; C x C motif chemokine; CC motif chemokine; CCmotif chemokine; chem; chemokine (C-X-C motif) ligand 13; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); CXC; CXC chemokine BLC; CXC motif chemokine; CXC motif chemokine 13; C-X-C motif chemokine 13; C-X-C motif chemokine ligand 13; CXCL; Cxcl13; SCYB13; small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant); small inducible cytokine subfamily B (Cys-X-Cys), member 13; small-inducible cytokine B13
Common Name CXCL13
Gene Symbol Cxcl13
Biological Activity Determined by its ability to chemoattract human B cells.
Conjugate Unconjugated
Recombinant Recombinant
Sequence ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.