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STEMCELL Technologies Mouse Recombinant IL-13

Product Code. 17179391
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Quantity:
10 μg
100 μg
Unit Size:
100µg
10µg
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Product Code. 17179391

Brand: STEMCELL Technologies 78030

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This item is not returnable. View return policy

Description

Interleukin 13

  • Interleukin 13 (IL-13) is a type I cytokine, and signals through type I cytokine receptors to activate JAK/STAT and IRS-1/IRS-2 pathways
  • IL-13 is produced by T cells and innate lymphoid cells (Pulendran & Artis) and it inhibits production of pro-inflammatory cytokines, prostaglandins, and reactive oxygen and nitrogen species by monocytes and macrophages (Hershey)
  • Unlike human B cells, IL-13 has no effect on mouse B cell development and function
  • IL-13 promotes eosinophil survival, activation, and recruitment, and also activates mast cells (Hershey)
  • IL-13 regulates gastrointestinal parasite expulsion, airway hyperresponsiveness, allergic inflammation, tissue eosinophilia, goblet cell hyperplasia, intracellular parasitism, tissue remodeling, tumor cell growth, and fibrosis
  • IL-13 induces hypercontractility of smooth muscles by directly acting on the muscle cells as well as the enteric nerves (Wynn)

Specifications

Name Interleukin-13, NC30
Quantity 100 μg
Cell Type B Cells; Hematopoietic Stem and Progenitor Cells; Monocytes
Purity or Quality Grade ≥95%
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