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STEMCELL Technologies Mouse Recombinant IL-5

Product Code. 17129441
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Quantity:
100 μg
25 μg
Unit Size:
100µg
25µg
This item is not returnable. View return policy

Product Code. 17129441

Brand: STEMCELL Technologies 78049

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This item is not returnable. View return policy

Description

Interleukin 5

  • Interleukin 5 (IL-5) is a member of the short-chain 4-α-helical bundle subset of hematopoietic cytokines
  • It binds to the specific α receptor, which in turn recruits the common β receptor that initiates signaling via JAK/STAT and MAPK pathways
  • IL-5 is produced by Th2 cells, eosinophils, activated mast cells, and ILC2 cells
  • IL-5 affects the differentiation, activation, and survival of eosinophils, thus playing an important role in allergic inflammation, asthma, and parasite immunity
  • Stimulation of eosinophils with IL-5 leads to their activation, upregulation of CD11b expression, and inhibition of apoptosis (Shearer)

Specifications

Name B cell differentiation factor II, BCDFII, EDF, Eosinophil differentiation factor, Interleukin-5, TFR
Quantity 100 μg
Cell Type B Cells; Granulocytes and Subsets; Hematopoietic Stem and Progenitor Cells
Purity or Quality Grade ≥95%
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