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STEMCELL Technologies Mouse Recombinant IL-6

Product Code. 17109451
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Product Code. 17109451

Brand: STEMCELL Technologies 78052

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Description

Interleukin 6

  • Interleukin 6 (IL-6) is a pleiotropic growth factor with a wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis
  • IL-6 is produced by a variety of cell types including T cells, B cells, monocytes and macrophages, fibroblasts, hepatocytes, vascular endothelial cells, and various tumor cell lines
  • On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells
  • In combination with cytokines such as IL-3, GM-CSF, and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro
  • IL-6 signals through a cell surface type I cytokine receptor complex consisting of the ligand-binding IL-6α (CD126) and the signal-transducing gp130 subunits
  • The binding of IL-6 to its receptor system includes activation of the JAK/STAT signaling pathway

Specifications

Name B cell differentiation factor, BSF-2, IFN-β2, Interleukin-6
Quantity 100 μg
Cell Type Airway Cells; B Cells; Hematopoietic Stem and Progenitor Cells; Intestinal Cells; Lymphocytes; Neurons; Pluripotent Stem Cells; T Cells
Purity or Quality Grade ≥95%
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