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STEMCELL Technologies Mouse Recombinant TPO

Product Code. p-7217826
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Quantity:
10 μg
1000 μg
50 μg
Unit Size:
1000µg
10µg
50µg
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Product Code. 17159501

Brand: STEMCELL Technologies 78072

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Description

Thrombopoietin

  • Thrombopoietin (TPO) is a key regulator of megakaryocytopoiesis and thrombopoiesis in vitro and in vivo
  • TPO stimulates the proliferation and maturation of megakaryocytes and has an important role in regulating the level of circulating platelets in vivo
  • TPO also promotes the survival, self-renewal, and expansion of hematopoietic stem cells and primitive multilineage progenitor cells
  • It is commonly used with other cytokines such as stem cell factor (SCF) and Flt3/Flk-2 Ligand to promote expansion of primitive hematopoietic cells in culture (Hitchcock & Kaushansky)
  • The TPO receptor, c-Mpl, is expressed at all stages of megakaryopoiesis, from hematopoietic stem and progenitor cells to mature platelets

Specifications

Name c-MPL ligand, Megakaryocyte colony-stimulating factor, MGDF
Quantity 50 μg
Cell Type Hematopoietic Stem and Progenitor Cells; Mesoderm, PSC-Derived; Pluripotent Stem Cells
Purity or Quality Grade ≥95%
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