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Gibco™ Mouse TFF-2 Recombinant Protein, PeproTech®

Product Code. 17812563
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Quantity:
1 mg
100 μg
20 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
1mg
20µg
250µg
500µg
5µg
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Product Code. 17812563

Brand: Gibco™ 31530100UG

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This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q03404
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 21785
Molecular Weight (g/mol) 11.9 kDa
Name Mouse TFF-2
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias mSP; pancreatic spasmolytic polypeptide; PSP; SML1; SP; spasmolysin; Spasmolytic polypeptide; spasmolytic protein 1; Tff2; Trefoil factor 2; trefoil factor 2 (spasmolytic protein 1)
Common Name TFF2
Gene Symbol Tff2
Conjugate Unconjugated
Recombinant Recombinant
Sequence EKPSPCRCSR LTPHNRKNCG FPGITSEQCF DLGCCFDSSV AGVPWCFHPL PNQESEQCVM EVSARKNCGY PGISPEDCAS RNCCFSNLIF EVPWCFFPQS VEDCHY
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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