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Invitrogen™ Mouse TPO (Thrombopoietin), AOF Recombinant Protein

Product Code. p-7203284
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Quantity:
1 mg
10 μg
100 μg
500 μg
Unit Size:
100µg
10µg
1mg
500µg
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Product Code. 17636565

Brand: Invitrogen™ RP87753

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Description

E. coli Recombinant Protein

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
  • Purity: >95% by SDS-Page
  • Endotoxin Concentration: AX41 ≤EUs/μg
  • Protein Length: 175 aa.
  • Biological Activity: <5 ng/mL
  • Molecular Weight: 18.7 kDa
  • Animal Origin Free: Yes
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P40226
For Use With (Application) Control, ELISA, Functional Assay, Gel Shift, Western Blot
Formulation 10 mM sodium phosphate with no preservative
Gene ID (Entrez) 21832
Molecular Weight (g/mol) 18.7 kDa
Name Mouse Thrombopoietin (TPO), AOF
Quantity 100 μg
Source E. coli
Storage Requirements -20°C
Regulatory Status RUO
Gene Alias C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDF; MKCSF; ML; MPL ligand; Mpllg; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; THCYT1; THPO; Thrombopoietin; TPO
Gene Symbol THPO
Specific Reactivity Mouse
Conjugate Unconjugated
Recombinant Recombinant
Form Lyophilized
Purity or Quality Grade >95%
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