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Tocris Bioscience™ MS 275
HDAC (Class I) inhibitor
Brand: Tocris Bioscience™ 6208/50
This item is not returnable.
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Description
MS 275 is a class I HDAC inhibitor (IC50 values are 0.18, 0.74, 44.9 and >100 μM for HDAC1, 3, 8 and 6, respectively). Exhibits antiproliferative effects and induces apoptosis in a range of tumor cell lines in vitro and in vivo. Increases estrogen receptor α- and aromatase expression in breast cancer cells. Inhibits PCB-induced neuronal cell death by preventing HDAC3 binding and histone deacetylation within the synapsin-1 promoter.Specifications
| (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate | |
| 209783-80-2 | |
| >99% | |
| 50 mg |
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