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Tocris Bioscience™ MS 275

Description
MS 275 is a class I HDAC inhibitor (IC50 values are 0.18, 0.74, 44.9 and >100 μM for HDAC1, 3, 8 and 6, respectively). Exhibits antiproliferative effects and induces apoptosis in a range of tumor cell lines in vitro and in vivo. Increases estrogen receptor α- and aromatase expression in breast cancer cells. Inhibits PCB-induced neuronal cell death by preventing HDAC3 binding and histone deacetylation within the synapsin-1 promoter.
Specifications
Specifications
| Chemical Name or Material | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate |
| CAS | 209783-80-2 |
| Assay Percent Range | >99% |
| Quantity | 10 mg |
| Molecular Formula | C21H20N4O3 |
| Formula Weight | Observed MW: 376.41 |
Product Title
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