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DiscoverX PathHunter™ CHO-K1 mMC4R β-Arrestin Cell Pool

Product Code. 17373519
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17373519

Brand: DiscoverX 930608P2

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This item is not returnable. View return policy

Description

The PathHunter™ CHO-K1 mMC4R β-Arrestin Cell Pool measures mMC4R (GPCR) activity via recruitment of β-Arrestin2. This cell pool ships as two vials of cryopreserved cells. Mouse protein.

The PathHunter™ mMC4R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-MSH) based activation of mMC4R GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged mMC4R and EA-tagged β-Arrestin 2. Activation of mMC4R stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable cell pool is provided as two vials of cryopreserved cells. Please note that this product expresses the mouse version of this protein.

Specifications

Assay Entry β-Arrestin recruitment
Cell Line CHO-K1
For Use With (Application) Cell Pools
Quantity 2 Vials
Target Entry mMC4R
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