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Paxillin Monoclonal Antibody (5H11), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen AHO0492

Additional Details : Weight : 0.50000kg

Product Code. 10018212

  • 429.00€ / Each
In Stock
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Description

Description

Staining of formalin-fixed, paraffin-embedded tissues requires boiling tissues in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at room temperature for 20 min. Recommended positive controls include HeLa cells and colon carcinoma.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
Specifications

Specifications

Paxillin
Monoclonal
0.2 mg/mL
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P49023, Q66H76, Q8VI36
PXN
Purified recombinant full-length human paxillin protein.
500 μL
Primary
Human, Mouse, Rat
Antibody
IgG1 κ
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
5H11
Unconjugated
PXN
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
Mouse
Protein G
RUO
19303, 360820, 5829
4° C
Liquid
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