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Eurofins DiscoverX PI3 Kinase (p110β/p85β) Mouse Protein

Product Code. 17300724
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
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Product Code. 17300724

Brand: Eurofins DiscoverX 14788

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This item is not returnable. View return policy

Description

Complex of N-terminal 6His-tagged, recombinant, full-length mouse p110β and untagged, recombinant, full length mouse p85β, for use in Kinase Assays.

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli.

GenBank NM_029094. The recombinant protein contains the amino acid substitution R123L (native protein coordinates) with respect toGenBank NM_029094, this is reported in the ESTs CV558291, CO431848, CN701015, CN681036, CN536135 and CN534564 / GenBank BC006796

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 125.5 kDa (p110β) and 81.4 kDa (p85β)
Quantity 10 μg
Species Murine
Recombinant Recombinant
Protein Tag N-terminal 6His / Untagged
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade Combined ≥72%
Protein PI 3-Kinase (p110β/p85β), murine
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