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![Invitrogen™ Human RAF1 (cRAF) [Y340D, Y341D], GST Tag Recombinant Protein 10μg](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Invitrogen™ Human RAF1 (cRAF) [Y340D, Y341D], GST Tag Recombinant Protein
Human RAF1 (cRAF) [Y340D, Y341D], GST Tag Recombinant Protein
Brand: Invitrogen™ PV3805
Additional Details : Weight : 0.05250kg
Description
RAF1 (cRAF) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylates and activates the serine⁄threonine specific protein kinases ERK1 and ERK2. The RAF1 Y340D Y341D mutant is constitutively active.Specifications
| NP_002871, Y340D, Y341D | |
| 4773, 5894 | |
| 10μg | |
| RAF Kinase Family | |
| Human | |
| GST Tag | |
| Biochemical terbium phospho-specific activity, Biochemical binding/kinetic | |
| Dry Ice | |
| RAF1 (cRAF) Y340D Y341D | |
| Baculovirus | |
| Recombinant, Catalytic, Mutant | |
| Serine/Threonine Kinases |
| Kinase Assay | |
| 66.4 kDa | |
| RAF1 (cRAF) Y340D Y341D | |
| aa 306-648; Y340D, Y341D | |
| Recombinant | |
| Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
|
| Ser⁄Thr Kinases: TKL Group | |
| LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate | |
| v-raf-1 murine leukemia viral oncogene homolog 1 | |
| Kinases & Inhibitors | |
| Liquid | |
| Signal Transduction |
For Research Use Only. Not for use in diagnostic procedures.