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enQuireBio™ Recombinant Chicken GH Antagonist Protein
A cDNA sequence encoding the GH Antagonist was constructed and used to recombinantly synthesize the protein.
137.00€ - 1285.00€
Specifications
| Name | GH Antagonist Protein |
|---|---|
| Regulatory Status | Research Use Only |
| Endotoxin Concentration | < 1.0 EU per ug protein as determined by the LAL method. |
| Biological Activity | Recombinant Chicken Growth Hormone G119R mutant did not bind to ovine GHR-ECD and was devoid of any biological activity in FDC-P1 3B9 cells. However, in binding experiments that were carried out using chicken liver membranes, both ovine GH and chicken GH showed similar IC50 values in competition with 125I-ovine GH, while the IC50 of G119R mutein was 10-fold higher. These results emphasize the importance of species specificity and indicate the possibility of antagonistic activity of chGH G119R in homologous system. |
| Product Type | Recombinant Protein |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15934498
|
enQuireBio™
QP10641-20UG |
20 μg |
137.00€
20µg |
Estimated Shipment: 18-06-2024 Log in to see stock. |
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|
15914498
|
enQuireBio™
QP10641-100UG |
100 μg |
212.00€
100µg |
Estimated Shipment: 18-06-2024 Log in to see stock. |
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|
15924498
|
enQuireBio™
QP10641-1MG |
1 mg |
1285.00€
1mg |
Estimated Shipment: 18-06-2024 Log in to see stock. |
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Specifications
| GH Antagonist Protein | |
| < 1.0 EU per ug protein as determined by the LAL method. | |
| Recombinant Protein | |
| E. coli | |
| The protein was lyophilized from a concentrated (1 mg/ml) solution with 0.3% NaHCO3 pH 8. |
| Research Use Only | |
| Recombinant Chicken Growth Hormone G119R mutant did not bind to ovine GHR-ECD and was devoid of any biological activity in FDC-P1 3B9 cells. However, in binding experiments that were carried out using chicken liver membranes, both ovine GH and chicken GH showed similar IC50 values in competition with 125I-ovine GH, while the IC50 of G119R mutein was 10-fold higher. These results emphasize the importance of species specificity and indicate the possibility of antagonistic activity of chGH G119R in homologous system. | |
| Chicken | |
| Untagged | |
| Greater than 98.0% as determined by:(a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE. |