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R&D Systems™ Recombinant Human Noggin Fc Chimera Protein

Product Code. 18736066
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Quantity:
100 μg
50 μg
500 μg
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100µg
500µg
50µg
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Product Code. 18736066

Brand: R&D Systems™ 3344NG100

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This item is not returnable. View return policy

Description

A New and Improved Noggin is Now Available! The new protein has ∼2 fold better activity, higher purity, and no tag! Earn double rewards for reviews

Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.100-0.400 µg/mL in the presence of 30 ng/mL of Recombinant Human BMP-4 (Catalog # 314-BP ).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q13253
For Use With (Application) Bioactivity
Gene ID (Entrez) 9241
Molecular Weight (g/mol) 49.6 kDa (monomer)
Name NOG, noggin, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1, SYNS1A
Quantity 100 μg
Source

Mouse myeloma cell line, NS0-derived human Noggin protein

Human Noggin (Gln28-Cys232) Accession # Q13253IEGRMDHuman IgG1 (Pro100-Lys330)N-terminus C-terminus
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Gene Symbol NOG
Conjugate Unconjugated
Species Human
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS.
Endotoxin Level <0.10 EU per 1 μg of the protein by the LAL method.
Purity or Quality Grade >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
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