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![RET [V804L] Recombinant Human Protein 10μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
RET [V804L] Recombinant Human Protein
RET [V804L] Recombinant Human Protein
Brand: Invitrogen PV4397
Additional Details : Weight : 0.00900kg
Description
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. The V804L mutant has been observed in association with cancer.Specifications
| NP_066124, V804L | |
| Pharma and Biopharma, Protein Assays and Analysis, Target and Lead Identification and Validation, Kinase Assay | |
| RET [V804L] Recombinant Human Protein | |
| –80°C | |
| 1 Each | |
| RET [V804L] Recombinant Human Protein | |
| RET | |
| RET [V804L] Recombinant Human Protein | |
| Human | |
| Baculovirus | |
| Receptor tyrosine kinases |
| 0.48mg/mL | |
| 79kDa | |
| 10μg | |
| For research use only. Not for use in diagnostic procedures | |
| RET V804L | |
| RET V804L was pre-diluted in enzyme dilution buffer and assayed in 25mM HEPES (pH 7.5), 10mM MgCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 1000μg/mL Abl1 peptide substrate (EAIYAAPFAKKK) and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| Amino acids 658-1114; V804L | |
| 1670nmoles of phosphate transferred to Abl1 peptide substrate (EAIYAAPFAKKK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1.67μg/mL | |
| GST Tag | |
| Kinase and inhibitors | |
| 90% by SDS-PAGE |
For Research Use Only. Not for use in diagnostic procedures.