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Tocris Bioscience™ SAHA

Description
SAHA inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and H4 in transformed cultured cells. Suppresses cell growth in a range of cancer cell lines; induces apoptosis in cutaneous T cell lymphoma cells in vitro. Activates autophagy. SAHA increases efficiency of transcription factor-induced reprogramming of mouse embryonic fibroblasts (MEF) to induced pluripotent stem cells (iPSC). Also enhances adeno-associated virus transduction of HeLa cells.
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 264.32 |
| Purity | >98% |
| Molecular Weight (g/mol) | 264.325 |
| Chemical Name or Material | SAHA |
Produkttitel
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