missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ SGC SMARCA-BRDVIII

Tocris Bioscience™ SGC SMARCA-BRDVIII
GREENER_CHOICE

Product Code. 18749536
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18749536

Brand: Tocris Bioscience™ 7460/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor

SGC-SMARCA-BRDVIII is a selective and high affinity SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomains (Kd(ITC) values are 35, 36 and 13 nM, respectively). SGC-SMARCA-BRDVIII exhibits selectivity over 25 other bromodomain families and shows no off-target activity on 85 protein kinases screened using temperature-shift binding assays. SGC-SMARCA-BRDVIII suppresses formation of 3T3-L1 mouse fibroblasts into adipocytes (EC50 <1.0 μM).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains
CAS 1997319-84-2
Quantity 10 mg
Target Bromodomain Inhibitors
Molecular Formula C19H25N5O3
Purity 0.98
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.