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Thrombospondin (TSP) Ab-3, Mouse Monoclonal Antibody,Lab Vision™ Epredia™
Provide accurate, reproducible results with the Epredia™ Thrombospondin (TSP) Ab-3, Mouse Monoclonal Antibody.
143.82€ - 724.20€
Specifications
| Antigen | Thrombospondin (TSP) Ab-3 |
|---|---|
| Clone | C6.7 |
| Applications | Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Concentration | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Concentration | Quantity | Price | Quantity & Availability | ||||
|
12681387
|
Epredia
MS-420-P1 |
200μg/mL | 500 μL |
419.00€
500µL |
Estimated Shipment: 10-06-2024 Log in to see stock. |
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|
12305103
|
Epredia
MS-420-P1ABX |
1mg/mL | 100 μL |
463.00€
100µL |
Estimated Shipment: 10-06-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | |||
|
12651387
|
Epredia
MS-420-P |
200μg/mL | 1 mL |
This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance. |
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|
12671387
|
Epredia
MS-420-P0 |
200μg/mL | 100 μL |
This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance. |
|||||
|
12691387
|
Epredia
MS-420-PABX |
1mg/mL | 200 μL |
This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance. |
|||||
Description
Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.Host Species: Mouse
Clone: C6.7
Isotype: IgG1
Species Reactivity: Human, Cow, Pig, Horse, Dog, Sheep and Rat. Others not known.
Epitope: Platelet- or cell-binding domain at the extreme C-terminus of TSP
Immunogen: Ca2+-replete, native purified human TSP from supernatant of thrombin-activated platelets
Molecular Weight: ∽450kDa (Nonreduced)
Cellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum, extracellular matrix Ab-3 shows no cross-reaction with fibronectin, fibrinogen, and von Willebrand factor. It blocks TSP-mediated agglutination of fixed RBCs. It shows no effect on TSP-mediated agglutination of fixed, activated platelets. It inhibits both thrombin- and A23187-induced aggregation of washed, live (not fixed) platelets without affecting the secretion of serotonin. It inhibits adhesion of melanoma G361 cells to TSP. It blocks binding of C-terminal domain to Integrin-Associated Protein (IAP)/CD47.
Recommended for:
- Immunohistochemistry (Not suitable)
- Western Blotting (Nonreduced only)
- Immunofluorescence
- Immunoprecipitation (Native verified)
- Electron Microscopy
- Flow Cytometry
- Blocks Binding of TSP-1 to IAP/CD47
Note:
USA: RUO; Int'l: RUO
Specifications
| Thrombospondin (TSP) Ab-3 | |
| Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Mouse | |
| Angiogenesis | |
| Ca2plus-replete, native purified human TSP from supernatant of thrombin-activated platelets | |
| Primary |
| C6.7 | |
| Monoclonal | |
| Concentrated | |
| RUO | |
| Bovine, Canine, Equine, Human, Porcine, Rat, Sheep | |
| IgG1 |