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TLR4/MD-2 Complex Rat anti-Mouse, Functional Grade, Clone: MTS510, eBioscience™

Rat Monoclonal Antibody

Marque:  Affymetrix eBioscience 16-9924-81

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15278837

  • 162.00€ / 50µg


Date dexpédition estimée
du fournisseur 26-09-2019
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Description

Description

Applications Tested: The MTS510 antibody has been tested by flow cytometric analysis of mouse peritoneal exudates cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Spécification

Spécification

TLR4/MD-2 Complex
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q9JHF9, Q9QUK6
Ly96, Tlr4
IgG2a, kappa
50 μg
4° C
Primary
17087, 21898
Flow Cytometry, Functional Assay, Neutralization
MTS510
Functional Grade
Tlr4
Liquid
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Vidéos
Documents

For Research Use Only.