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DiscoverX cAMP Hunter™ eXpress ADRA2C CHO-K1 GPCR Assay

Product Code. 17374469
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17374469

Brand: DiscoverX 950053E2CP2M

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This item is not returnable. View return policy

Description

The cAMP Hunter™ eXpress ADRA2C CHO-K1 GPCR Assay measures ADRA2C (GPCR) activity via decreased levels of intracellular cAMP. eXpress kits contain all assay materials: cells, reagents, and plates.

The cAMP Hunter™ ADRA2C eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. epinephrine and norepinephrine) based activation of ADRA2C GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype ADRA2C , a naturally Gi/Go coupled GPCR. Upon activation of ADRA2C , the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry CHO-K1
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist UK 14,304
Quantity 200 dp (2 x 96-well)
Target Entry ADRA2C
Cell Line CHO-K1
Target ADRA2C
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