Benzenesulfonamides
Tolazamide, TRC
CAS: 1156-19-0 Molecular Formula: C14 H21 N3 O3 S Molecular Weight (g/mol): 311.4 Synonym: Benzenesulfonamide, N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-,Urea, 1-(hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)- (6CI,7CI,8CI),1-(4-Methylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea,1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea,1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea,Diabewas,N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea,NSC 70762,Norglycin,Tolanase,Tolazamide,Tolinase,U 17835 IUPAC Name: 1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea SMILES: Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2
Levopride, TRC
CAS: 23672-07-3 Molecular Formula: C15 H23 N3 O4 S Molecular Weight (g/mol): 341.43 Synonym: 5-(Aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxybenzamide,Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-, (S)-,o-Anisamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-, (-)- (8CI),(-)-Sulpiride,L-Sulpiride,Lesuride,Levobren,Levopraid,Levosulpiride,S-(-)-Sulpiride,S-Sulpiride,l-Sulpiride,levopride,sulpid IUPAC Name: N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide SMILES: CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N
Gliclazide, TRC
CAS: 21187-98-4 Molecular Formula: C15 H21 N3 O3 S Molecular Weight (g/mol): 323.41 Synonym: Gliclazide,N-[[(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methylbenzenesulfonamide,1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea,Cyclopenta[c]pyrrole benzenesulfonamide deriv.,1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea,Diabezidum,Diabrezide,Diamicron,Diaprel,Glimicron,Glinormax,Glyzide,N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea,S 1702,S 852,SE 1702 IUPAC Name: 1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea SMILES: Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2
Mefruside, TRC
CAS: 7195-27-9 Molecular Formula: C13 H19 Cl N2 O5 S2 Molecular Weight (g/mol): 382.88 Synonym: 4-Chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]-1,3-benzenedisulfonamide,4-Chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)-m-benzenedisulfonamide,B 1500,BAY 1500,Baycaron,FBA 1500,FDA 1902,Mefrusid,Mefruside,N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine,N-(4'-Chloro-3'-sulfamoylbenzenesulfonyl)-N-methyl-2-aminomethyl-2-methyltetrahydrofuran IUPAC Name: 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,3-disulfonamide SMILES: CN(CC1(C)CCCO1)S(=O)(=O)c2ccc(Cl)c(c2)S(=O)(=O)N
Glimepiride, TRC
CAS: 93479-97-1 Molecular Formula: C24 H34 N4 O5 S Molecular Weight (g/mol): 490.62 Synonym: 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-,1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-, trans-,3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide,Amaryl,Diameprid,Dibiglim,Glimax,Glimepiride,Glimperide,Glirid,GlucoNovax,HOE 490,Limeral,trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl] 2-oxo-1H-pyrrole-1-carboxamide IUPAC Name: 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide SMILES: CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@@H]3CC[C@@H](C)CC3)C1=O
Methisosildenafil, TRC
CAS: 496835-35-9 Molecular Formula: C23 H32 N6 O4 S Molecular Weight (g/mol): 488.6 Synonym: 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[5-[[(3R,5S)-3,5-dimethyl-1-piperazinyl]sulfonyl]-2-ethoxyphenyl]-1,6-dihydro-1-methyl-3-propyl-, rel-,Piperazine, 1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-3,5-dimethyl-, (3R,5S)-rel- (9CI),Aildenafil,Methisosildenafil IUPAC Name: 5-[5-[(3S,5R)-3,5-dimethylpiperazin-1-yl]sulfonyl-2-ethoxyphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one SMILES: CCCc1nn(C)c2C(=O)NC(=Nc12)c3cc(ccc3OCC)S(=O)(=O)N4C[C@@H](C)N[C@@H](C)C4
Carbutamide, TRC
CAS: 339-43-5 Molecular Formula: C11 H17 N3 O3 S Molecular Weight (g/mol): 271.34 Synonym: Benzenesulfonamide, 4-amino-N-[(butylamino)carbonyl]-,Sulfanilamide, N1-(butylcarbamoyl)- (6CI),Urea, 1-butyl-3-sulfanilyl- (7CI,8CI),1-Butyl-3-sulfanilylurea,Alentin,Aminophenurobutane,BZ 55,Bucarban,Bucrol,Bukarban,Burcol,Butisulfina,Carbutamid,Carbutamide,Diaboral,Emedan,Glucidoral,Glucofren,Glybutamide,Inbuton,Invenol,N-(4-Aminobenzenesulfonyl)-N'-butylurea,N-Butyl-N'-sulfanilylurea,N-Sulfanilyl-N'-butylurea,NSC 242409,NSC 246862,Nadisan,Nadizan,Norboral,N'-(4-Aminobenzenesulfonyl)-N-butylurea,N'-(4-Aminophenylsulfonyl)-N-butylurea,N'-(4-Aminophenylsulfonyl)-N-n-butylurea,N'-(Butylcarbamoyl)sulfanilamide,Oranil,Oranyl,Orasulin,U 6987 IUPAC Name: 1-(4-aminophenyl)sulfonyl-3-butylurea SMILES: CCCCNC(=O)NS(=O)(=O)c1ccc(N)cc1
Chlorpropamide, TRC
CAS: 94-20-2 Molecular Formula: C10 H13 Cl N2 O3 S Molecular Weight (g/mol): 276.74 Synonym: Urea, 1-[(p-chlorophenyl)sulfonyl]-3-propyl- (8CI),4-Chloro-N-[(propylamino)carbonyl]benzenesulfonamide,1-(p-Chlorobenzenesulfonyl)-3-propylurea,1-(p-Chlorophenylsulfonyl)-3-propylurea,1-Propyl-3-(p-chlorobenzenesulfonyl)urea,Adiaben,Asucrol,Catanil,Chlorodiabina,Chloronase,Chloropropamide,Chlorpropamid,Chlorpropamide,Diabaril,Diabechlor,Diabenal,Diabenese,Diabeneza,Diabet-Pages,Diabetoral,Diabinese,Glisema,Meldian,Melitase,Millinese,N-(4-Chlorophenylsulfonyl)-N'-propylurea,N-(p-Chlorobenzenesulfonyl)-N'-propylurea,N-Propyl-N'-(p-chlorobenzenesulfonyl)urea,N-Propyl-N'-p-chlorphenylsulfonylcarbamide,NSC 44634,NSC 626720,P 607,Pamidin,Stabinol,U 9818 IUPAC Name: 1-(4-chlorophenyl)sulfonyl-3-propylurea SMILES: CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
Parecoxib, TRC
CAS: 198470-84-7 Molecular Formula: C19 H18 N2 O4 S Molecular Weight (g/mol): 370.42 Synonym: Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-,N-[[4-(5-Methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]propanamide,Parecoxib,SC 69124,Valus-P,Vorth-P IUPAC Name: N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide SMILES: CCC(=O)NS(=O)(=O)c1ccc(cc1)c2c(C)onc2c3ccccc3
Descarbonsildenafil, TRC
CAS: 1393816-99-3 Molecular Formula: C21H30N6O4S Molecular Weight (g/mol): 462.57 Synonym: Benzenesulfonamide, 3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(dimethylamino)ethyl]-4-ethoxy-,Descarbonsildenafil,Sildenafil descarbon IUPAC Name: N-[2-(dimethylamino)ethyl]-4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide SMILES: CCCc1nn(C)c2C(=O)NC(=Nc12)c3cc(ccc3OCC)S(=O)(=O)NCCN(C)C
Udenafil, TRC
CAS: 268203-93-6 Molecular Formula: C25 H36 N6 O4 S Molecular Weight (g/mol): 516.66 Synonym: Benzenesulfonamide, 3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxy-,Benzenesulfonamide, 3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxy- (9CI),DA 8159,Udenafil,Zydena IUPAC Name: 3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzenesulfonamide SMILES: CCCOc1ccc(cc1C2=Nc3c(CCC)nn(C)c3C(=O)N2)S(=O)(=O)NCCC4CCCN4C
Clofenamide, TRC
CAS: 671-95-4 Molecular Formula: C6 H7 Cl N2 O4 S2 Molecular Weight (g/mol): 270.71 Synonym: 4-Chloro-1,3-benzenedisulfonamide,4-Chloro-m-benzenedisulfonamide,4-Chloro-m-benzenedisulfonamide,4-Chlorobenzene-1,3-disulfonamide,Aponiere,Aquedux,Clofenamidum,Diumide,Diuretic 2822,Eleklin,Frictan,Haflutan,Indigatin,Macashi,Monochlorphenamide,Salco,Saltron,Salzen,Soluran; IUPAC Name: 4-chlorobenzene-1,3-disulfonamide SMILES: NS(=O)(=O)c1ccc(Cl)c(c1)S(=O)(=O)N
Sulfamethazine, TRC
CAS: 57-68-1 Molecular Formula: C12 H14 N4 O2 S Molecular Weight (g/mol): 278.33 Synonym: Sulfanilamide, N1-(4,6-dimethyl-2-pyrimidinyl)- (8CI),2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine,2-(4-Aminobenzenesulfonylamino)-4,6-dimethylpyrimidine,2-(p-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine,2-Sulfanilamido-4,6-dimethylpyrimidine,4,6-Dimethyl-2-sulfanilamidopyrimidine,4-Amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide,4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide,4-Amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide,A 502,Azolmetazin,BN 2409,Calfspan,Calfspan Tablets,Cremomethazine,Diazil,DiazilSulfadine,Diazyl,Dimezathine,Dimidin R,Kelametazine,Mermeth,N-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide,N1-(4,6-Dimethyl-2-pyrimidinyl)sulfanilamide,N1-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide,NSC 67457,NSC 683529,Neasina,Neazina,Panazin,Pirmazin,S-Dimidine,Spanbolet,SulfaSURE SR Bolus,Sulfadimerazine,Sulfadimesin,Sulfadimesine,Sulfadimethyldiazine,Sulfadimethylpyrimidine,Sulfadimezin,Sulfadimezine,Sulfadimidin,Sulfadimidine,Sulfadine,Sulfamethazine,Sulfamethiazine,Sulfodimesin,Sulfodimezine,Sulka K Boluses,Sulphadimethylpyrimidine,Sulphadimidine,Sulphamethasine,Sulphamethazine,Sulphamezathine,Sulphamidine,Sulphodimezine,Superseptil,Superseptyl,Sustain III,Vertolan,Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)- IUPAC Name: 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide SMILES: Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
Glisoxepid, TRC
CAS: 25046-79-1 Molecular Formula: C20 H27 N5 O5 S Molecular Weight (g/mol): 449.52 Synonym: 3-Isoxazolecarboxamide, N-[2-[4-[[[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-,Urea, 1-(hexahydro-1H-azepin-1-yl)-3-[[p-[2-(5-methyl-3-isoxazolecarboxamido)ethyl]phenyl]sulfonyl]- (8CI),N-[2-[4-[[[[(Hexahydro-1H-azepin-1-yl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-3-isoxazolecarboxamide,4-[4-[β-(5-Methylisoxazole-3-carboxamido)ethyl]phenylsulfonyl]-1,1-hexamethylenesemicarbazide,BS 4231,Glisepin,Glisoxepid,Glisoxepide,Pro-Diaban,Pro-Diaben,RP 22410 IUPAC Name: N-[2-[4-(azepan-1-ylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide SMILES: Cc1onc(c1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NN3CCCCCC3
Sulfameter, TRC
CAS: 651-06-9 Molecular Formula: C11 H12 N4 O3 S Molecular Weight (g/mol): 280.3 Synonym: Sulfameter,Sulfameter IUPAC Name: 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide SMILES: COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1