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Karl Fischer Buffers and Reagents

Karl Fischer Buffers and Reagents

Karl Fischer (KF) titration is a trusted method for precise water determination across pharmaceuticals, chemicals, food, and research labs. In this category you’ll find Karl Fischer buffers, reagents, and supporting solutions designed to improve endpoint stability, reduce drift, and help you achieve repeatable moisture results. Explore options for coulometric and volumetric workflows from leading suppliers including Fisher Chemicals, Honeywell Fluka, Honeywell Research Chemicals, and JT Baker—with formats suited for routine QC and advanced method development.

HYDRANAL™ – Coulomat AG-Oven, Reagent for Coulometric KF Titration With Oven (Anolyte Solution), for Cells With and Without Diaphragm, Honeywell Fluka

500mL HYDRANAL-Coulomat AG-Oven reagent for coulometric KF titration with oven (anolyte solution).

HYDRANAL™ - Coulomat AG-Oven, Reagent for coulometric KF titration with oven (anolyte solution), for cells with and without diaphragm, Honeywell Fluka

Karl Fischer Aqualine™ Complete 5, for Karl Fischer Titration By Volumetry, Fisher Chemical™

Single-component volumetric reagent for high water content analysis.

Karl Fischer Aqualine™ Complete 5, for Karl Fischer Titration By Volumetry, Fisher Chemical™

Acetonitrile 50%, Water 47.5 % and Trifluoroacetic Acid 2.5%, for Mass Spectrometry, Honeywell Riedel-de Haën™

LabReady™ Solvent Blend, for mass spectrometry.

Acetonitrile 50%, Water 47.5 % and Trifluoroacetic acid 2.5%, For mass spectrometry, Honeywell Riedel-de Haën™

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Speed Up KF Titrations With Trusted Reagents

Keep moisture determinations consistent with high-quality Karl Fischer solutions selected for routine workflows and reliable endpoints.

Speed up KF titrations with trusted reagents

Build a Dependable KF Workflow

From coulometric reagents to volumetric composites, choose formulations that help control drift and support repeatable moisture results.

Build a dependable KF workflow

Must Have

FAQ

Karl Fischer buffers and reagents are used to measure water content (moisture) in liquids and solids by KF titration. They support stable reaction conditions, clear endpoints, and repeatable results. Popular options include formulations from Fisher Chemicals, Honeywell Fluka, Honeywell Research Chemicals, and JT Baker for routine QC and method development.

Choose coulometric reagents for low water levels (trace moisture), where generated iodine enables highly sensitive measurement. Use volumetric reagents for higher water content ranges and faster throughput with direct titrant addition. Selecting matched anolyte/catholyte or composite reagents from Honeywell Fluka or Fisher Chemicals helps maintain consistency across instruments and sample types.

Drift control often improves when you use fresh, properly matched KF solutions and limit moisture ingress. High-quality anolyte/catholyte pairs or composite volumetric reagents can help stabilize baselines and endpoints. Many labs standardize on well-known product lines from Honeywell Fluka, JT Baker, or Fisher Chemicals to improve repeatability across operators and sites.

Store KF reagents tightly sealed, away from humidity and heat, and follow the manufacturer’s guidance for temperature and shelf-life. Minimize bottle opening time and use dry handling techniques to avoid water uptake. Using consistent supplies from Fisher Chemicals, Honeywell Fluka, or JT Baker helps maintain method control and reduces troubleshooting from aged or contaminated reagent.

In coulometric KF titration, the anolyte and catholyte support the electrochemical generation and consumption of iodine. Using the correct pairing helps maintain conductivity, stable reaction conditions, and accurate moisture results—especially for challenging matrices. Suppliers such as Honeywell Fluka provide dedicated coulometric solutions (including oven variants) to match common instrument setups.

Start by matching your method type (coulometric or volumetric), your sample introduction (direct or oven), and your instrument recommendations. This category includes widely used solutions and composites from Fisher Chemicals, Honeywell Fluka, Honeywell Research Chemicals, and JT Baker. Filter by brand and compare formulations to align with your SOP and target moisture range.

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