Isopropanols

Isopropanol and 2-propanol are the same chemical (also called propan-2-ol or IPA). Labels vary by supplier and grade, but the solvent is identical in identity. Choose based on purity and application needs, such as Fisher Chemical HPLC grade or Honeywell LC/MS options for sensitive analytical work.

For chromatography, select HPLC-grade isopropanol to help minimise impurities that can affect baseline stability and retention. Look for consistent specifications and documentation. Fisher Chemical and Honeywell chromatography grades are commonly used when reproducibility matters, especially for routine HPLC methods and validated workflows.

LC/MS-grade isopropanol is designed to reduce non-volatile residues and background signals that can suppress ionisation. Choose LC/MS-labelled products (for example, Honeywell CHROMASOLV LC-MS) when running trace-level assays, cleaning LC/MS systems, or preparing mobile phases where sensitivity and cleanliness are critical.

Water content can impact moisture-sensitive reactions, cleaning performance, and chromatography results. Higher water can change elution strength and affect separation consistency. If water control matters, choose documented grades from suppliers such as Honeywell Research Chemicals or Fisher Chemical, and confirm suitability for your method requirements.

Store isopropanol tightly closed in a cool, well-ventilated area away from ignition sources, following your site safety procedures and the SDS. Keep containers sealed to reduce contamination and water uptake. Larger pack sizes from Fisher Chemical, Honeywell Fluka, or JT Baker can support lab stocking when managed under flammables storage rules.

IPA is widely used for cleaning glassware and instruments, solvent rinsing, sample preparation, and chromatography workflows. HPLC and LC/MS grades support analytical methods, while ACS/analytical grades suit routine lab tasks. Brands like Fisher Chemical and JT Baker offer options across grades and volumes for different lab needs.

Many labs standardise on established suppliers for consistent specifications and availability. Fisher Chemical is frequently chosen for chromatography and general lab grades, Honeywell (including Fluka and Research Chemicals) for analytical and LC/MS options, and JT Baker for high-quality solvents supporting regulated or method-driven environments.