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R&D Systems™ 2-APB

Product Code. 18075342
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18075342 10 mg 10mg
18034702 50 mg 50mg
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Product Code. 18075342 Supplier R&D Systems™ Supplier No. 1224/10
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Beschreibung

A Tocris product, part of R&D Systems. IP3 receptor antagonist. Also TRP channel modulator

A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42 μM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10 μM) and inhibits it at higher concentrations (up to 50 μM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes.
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 524-95-8
Molecular Formula C14H16BNO

Spezifikation

Quantity 10 mg
Product Line Tocris
Formula Weight 225.1
Purity >98%
Molecular Weight (g/mol) 225.10
Chemical Name or Material 2-APB
Name des Produkts
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