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2-Cyanoethyl diisopropylchlorophosphoramidite, 95%
Descripción
2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3'-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
2-Cyanoethyl diisopropylchlorophosphoramidite is a useful intermediate in organic synthesis. It acts as a protecting reagent in DNA synthesis. It is involved in the selective monophosphorylation of carbohydrates and nucleosides. It plays an essential role in the conversion of protected ribonucleosides to phosphoramidites. It is also utilized as phosphitylating reagent for 3′-hydroxyl groups in the synthesis of oligodeoxyribonucleotides.
Solubility
Miscible with chloroform and dichloromethane.
Notes
Reacts violently with water. Incompatible with alcohols and strong bases.
Especificaciones
Especificaciones
| Density | 1.061 |
| Boiling Point | 103°C to 105°C (0.08 mmHg) |
| Flash Point | >110°C (230°F) |
| Refractive Index | 1.478 |
| Quantity | 5 g |
| UN Number | UN2845 |
| Beilstein | 3588525 |
| Sensitivity | Moisture sensitive |
| Solubility Information | Miscible with chloroform and dichloromethane. |
| Formula Weight | 236.68 |
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Seguridad y manipulación
- 2-Cyanoethyl diisopropylchlorophosphoramidite
- Danger
- Serious eye damage/eye irritation Category 1
- Pyrophoric liquid Category 1
- Skin corrosion/irritation Category 1 B
- H250-Catches fire spontaneously if exposed to air.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P231+P232-Handle under inert gas. Protect from moisture.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P334-IF ON SKIN: Immerse in cool water/wrap in wet bandages.
- P310-Immediately call a POISON CENTER/doctor/.
- P402+P404-Store in a dry place. Store in a closed container.
- MIXTURE LIST-Contain: 2-Cyanoethyl diisopropylchlorophosphoramidite
RUO – Research Use Only
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