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Tocris Bioscience™ 3-Deazaneplanocin A hydrochloride
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Product Code. 30001570
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price
Product Code. 30001570 Supplier Tocris Bioscience™ Supplier No. 4703/1
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    280.00€
    264.60€ / 1mg
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Estimated Shipment: 16-09-2026
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186.67 EUR valid until 2026-09-30
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price

Beskrivning

EZH2 histone methyltransferase inhibitor

3-Deazaneplanocin A hydrochloride is a histone methyltransferase inhibitor; decreases global histone methylation. 3-Deazaneplanocin A hydrochloride inhibits EZH2 histone methyltransferase and s-adenosylhomocysteine (SAH) hydrolase activity. Blocks trimethylation of lysine 27 on histone H3 and lysine 20 on histone H4 in vitro. 3-Deazaneplanocin A hydrochloride induces apoptosis in multiple cancer cell lines and has no apoptotic effect on normal cells. Enhances Oct4 expression in chemically induced pluripotent stem cells (CiPSCs).

DZNep synthesized to Ancillary Material Grade also available.

For more information about how 3-Deazaneplanocin A hydrochloride may be used, see our protocol: Highly Efficient Generation of CiPSCs from MEFs

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Specifikationer

CAS 120964-45-6
Quantity 1 mg
Molecular Formula C12H15ClN4O3
Formula Weight 298.73
Purity >98%
Molecular Weight (g/mol) 298.727
Chemical Name or Material 3-Deazaneplanocin A hydrochloride
Produkttitel
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