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4,4'-Diaminodiphenyl sulfone, 98%

Product Code. 11493208
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Product Code. 11493208 Supplier Thermo Scientific Alfa Aesar Supplier No. A18976.22
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CAS: 80-08-0 | C12H12N2O2S | 248.3 g/mol

It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO, ethanol and acetone.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 80-08-0
Molecular Formula C12H12N2O2S
Molecular Weight (g/mol) 248.3
MDL Number MFCD00007887
InChI Key MQJKPEGWNLWLTK-UHFFFAOYSA-N
Synonym dapsone, diaphenylsulfone, 4,4'-diaminodiphenyl sulfone, dapson, 4,4'-sulfonyldianiline, diaphenylsulfon, sulfona, 4-aminophenyl sulfone, avlosulfone, diphenasone
PubChem CID 2955
ChEBI CHEBI:4325
IUPAC Name 4-(4-aminophenyl)sulfonylaniline
SMILES C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N

Specifications

Melting Point 175°C to 178°C
Odor Odorless
Quantity 100 g
Beilstein 788055
Merck Index 14,2822
Solubility Information Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO,ethanol and acetone.
Formula Weight 248.3
Percent Purity 98%
Chemical Name or Material 4,4'-Diaminodiphenyl sulfone

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